The inaugural members of the MCHRI consist of research centres and/or programs that existed at McMaster University and McMaster Children's Hospital before the conception of the Institute or are new entities grown out of the collaborative work of MCHRI. These members conduct research in multiple areas of child health and development. They have come together as a federated group under the umbrella of the Institute, while continuing to maintain their original identity and research focus. Bringing these research centres/programs together will allow them to develop formal research partnerships with each other and with external partners, and leverage research knowledge and funding which would not be possible without the MCHRI.
The MCHRI members are:
- CanChild Centre for Childhood Disability Research: Founded in 1989, CanChild is a research and educational centre focused on issues that will make a difference for children and youth with physical, developmental and communication needs and their families. It has become an international leader in the field of childhood disability through innovative research and a commitment to making research findings easily accessible to many audiences
- Cardiometabolic Health in Youth Program: This program includes clinical and research components with the common aim of improving the metabolic health in children with disorders of cholesterol metabolism and children with obesity-related health problems.
- Childhood Cancer Program: This program is leading the field by bringing together quality of life assessments with treatment regimens. Doing so gives researchers and caregivers a greater understanding of the long-term needs of these children, meaning better service for this population.
- Children's Exercise and Nutrition Centre (CENC): CENC is considered to be a leading research centre in the study of the effects of physical activity (and inactivity) on the physical and mental health of children
- Molecular Mechanisms of Obesity:lead by Dr. Sandeep Raha, this program studies how obesity can signal changes in energy balance in various tissues such as fat, the heart, liver and pancreas. By better understanding routes to obesity related disorders, it is possible to develop more effective therapeutic strategies. Dr. Raha is also studying molecular mechanisms of how maternal obesity translates to increased risk for the fetus; and the consequences of childhood obesity on physiological development and health outcomes in later life.
- Neonatal follow-up Program: This program conducts follow-up assessments of high-risk infants to advance clinical understanding of the health outcomes of high-risk infants. The program has undertaken a ground-breaking series of studies to describe the outcome, to adulthood, of a population-based cohort of infants who weighed less than one kilogram at birth
- Neuromuscular/ Neurometabolic Research Centre: The clinic provides a world-renowned program that conducts leading research concerning neuromuscular and Neurometabolic disorders involving the evaluation of novel treatment strategies
- Nutrition and Bone Metabolism Program: This is an internationally recognized research program in pediatric nutrition, skeletal development and long-term health outcomes. Current research focuses on the concept that metabolic regulation can be programmed by nutritional and environmental exposures during fetal and neonatal life and that these can alter growth and development and increase the risk of adult-onset disease
- Offord Centre for Child Studies: Building on the legacy of its founder, the late Dr. David (Dan) Offord, the Centre focuses its research on early child development and works to understand why some children grow up to be healthy, well-adjusted adults while others appear to have a more difficult time growing up. Among their special foci are the genetic underpinnings and early presentation of childhood autism, childhood affective disorders, child maltreatment and family violence, and conduct disorders of childhood
- System-Linked Research Unit on Health and Social Service Utilization: Funded by the Ministry of Health and Long-Term Care since 1991, the mandate of this Research Unit is to assist community partners and help health and social service agencies create new solutions for problems affecting vulnerable children, youth, adults and seniors. The researchers are working to see what effects could be achieved at what cost through proactive coordinated and comprehensive approaches created by strategic alliances.